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  4. Recombinant Pig Interferon-induced GTP-binding protein Mx1 (MX1), partial

Recombinant Pig Interferon-induced GTP-binding protein Mx1 (MX1), partial

  • 中文名稱：
    野豬MX1重組蛋白
  • 貨號：
    CSB-YP015249PI
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    野豬MX1重組蛋白
  • 貨號：
    CSB-EP015249PI
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    野豬MX1重組蛋白
  • 貨號：
    CSB-EP015249PI-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    野豬MX1重組蛋白
  • 貨號：
    CSB-BP015249PI
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    野豬MX1重組蛋白
  • 貨號：
    CSB-MP015249PI
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    MX1; Interferon-induced GTP-binding protein Mx1; Myxoma resistance protein 1; Myxovirus resistance protein 1
  • 種屬：
    Sus scrofa (Pig)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Interferon-induced dynamin-like GTPase with antiviral activity against influenza A virus, (IAV). Inhibits IAV replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles.
  • 基因功能參考文獻(xiàn)：
    1. The deletion/insertion polymorphism in exon 14 of the Mx1 gene, which causes a frame shift, showed no significant association with growth or viremia after PRRSV infection. PMID: 26711047
    2. the SINE insertion polymorphism at site -547 of the MX1 gene promoter region is a potential DNA marker for porcine reproductive and respiratory syndrome resistance PMID: 26095790
    3. Overexpression of porcine Mx1 induce a robust immune response against foot-and-mouth disease virus. PMID: 26047650
    4. Studied the effects of porcine Mx1 protein on FMDV and BVDV replication by measuring viral reverse transcriptase activity at various time intervals. PMID: 25153459
    5. Polymorphisms in Mx1 are significantly associated with immunological traits in Landrace piglets and have potential application value for marker-assisted selection of pig breeding with disease resistance. PMID: 21667240
    6. Porcine Mx1 protein inhibits replication of influenza A virus, and impairs the traffic of the endocytic vesicles to the late endosomes. PMID: 20167191
    7. The 11-bp deletion Mx1 mutant is lacking antiviral activity able to contribute to the interference of influenza virus replication. PMID: 17203407
    8. Data showed that there were abundant MX1 gene polymorphisms in all pig breeds. PMID: 17650486
    9. Sequencing of the 332-bp MX1 promoter region identified 15 substitutions and insertions at three positions in 21 pigs from 15 breeds, in which nine genotypes were classified. PMID: 18254733

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  • 亞細(xì)胞定位：
    Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region.
  • 蛋白家族：
    TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family
  • 數(shù)據(jù)庫鏈接：

    KEGG: ssc:397128

    STRING: 9823.ENSSSCP00000029166

    UniGene: Ssc.221



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